Two Phase 2 readouts ahead as MapLight says cash lasts through 2027

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MapLight Therapeutics (NASDAQ: MPLT) reported its Q4 and full-year 2025 financial results, concluding the year with $453.1 million in cash, cash equivalents, and investments, which is projected to fund operations through 2027. The company is advancing several clinical trials, with topline results for two key Phase 2 studies, ZEPHYR (schizophrenia) and IRIS (autism spectrum disorder), anticipated in Q3 2026. Despite increased R&D and G&A expenses and a wider net loss in 2025 due to clinical development and IPO-related costs, MapLight emphasizes its strong financial position and strategic clinical milestones for the upcoming year.

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